Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer

Nature Biomedical Engineering 2026 Open access

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Authors: Gregory M. Chen, Ankita Jain, David T. Gering, Javier Satulovsky, Sarbani Datta, Peng Lai, Jayashree Karar, Vanessa Gonzalez, Kathleen A. Alexander, Anne Chew, Julie K. Jadlowsky, Marco Ruella
+25 more Luca Paruzzo, Kevin R. Amses, Andrew J. Rech, Edward A. Stadtmauer, Noelle V. Frey, Elizabeth O. Hexner, David L. Porter, Adam D. Cohen, Saar Gill, Alfred L. Garfall, S. J. Schuster, Kelvin C. Mo, Samantha I. Liang, Marko Spasic, Bruce L. Levine, Don L. Siegel, Ángel Ramírez-Fernández, Christopher R. Cabanski, Enjun Yang, Crystal L. Mackall, Frederic D. Bushman, Zinaida Good, E. John Wherry, Carl H. June, Joseph A. Fraietta
DOI: 10.1038/s41551-026-01633-7
Cited by: 9
References: 60

Fields of Study & Subjects

CAR-T cell therapy research Single-cell and spatial transcriptomics Immunotherapy and Immune Responses

Publication details

Journal / source
Nature Biomedical Engineering
Publisher
Springer Science and Business Media LLC
Volume
10
Issue
4
Pages
803–814
Publication date
9 March 2026
Language
EN