Non-viral targeted integration of large DNA in primary human T cells independent of double-stranded DNA breaks

Nature Biomedical Engineering 2026

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Authors: Sen Fang, Na Tang, Yiyun Li, Shuyu Guo, Yangcan Chen, Xin Wang, Xueke Li, Yu Hu, Jiawei Hao, Jianmin Wu, Qi Zhou, H WANG
+2 more Chenxin Wang, Wei Li
DOI: 10.1038/s41551-026-01671-1
Cited by: 6
References: 72

Fields of Study & Subjects

CRISPR and Genetic Engineering CAR-T cell therapy research Virus-based gene therapy research

Publication details

Journal / source
Nature Biomedical Engineering
Publisher
Springer Science and Business Media LLC
Publication date
30 April 2026
Language
EN