Inhibiting macrophage-derived lactate transport restores cGAS–STING signalling and enhances antitumour immunity in glioblastoma

Nature Cell Biology 2026

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Authors: Daqi Li, Gaoyuan Cui, Kailin Yang, Chenfei Lu, Yue Jiang, L Zhang, Qiulian Wu, Deobrat Dixit, Zhe Zhu, Ryan C. Gimple, Danling Gu, Jiancheng Gao
+18 more Qiankun Lin, Hang Yu, Zhumei Shi, Yun Chen, Qianghu Wang, Guangfu Jin, Fan Lin, Junfei Shao, Qigang Zhou, C C Liu, Chaojun Li, Yongping You, Nu Zhang, Junxia Zhang, Xu Qian, Q. Zhang, Jeremy N. Rich, Xiuxing Wang
DOI: 10.1038/s41556-025-01839-y
Cited by: 31
References: 60

Fields of Study & Subjects

interferon and immune responses Immune cells in cancer Cancer Hypoxia and Metabolism

Publication details

Journal / source
Nature Cell Biology
Publisher
Springer Science and Business Media LLC
Volume
28
Issue
2
Pages
349–362
Publication date
6 January 2026
Language
EN