Glucosylceramide-induced ectosomes propagate pathogenic α-synuclein in Parkinson’s disease

Nature Cell Biology 2026

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Authors: Julie Jacquemyn, Brian Marriott, Jinlan Chang, Ehlam Iftikhar, Ki Wai Chik, Nathanael Y. J. Lee, Luis F Rubio Atonal, Ceili Green, Jeremy Wong, Claudia Acevedo-Morantes, Carol X.‐Q. Chen, Michaël Nicouleau
+6 more Zhipeng You, Éric Deneault, Narges Abdian, Thomas M. Durcan, Jesse Jackson, Maria S. Ioannou
DOI: 10.1038/s41556-026-01871-6
Cited by: 7
References: 112

Fields of Study & Subjects

Parkinson's Disease Mechanisms and Treatments Lysosomal Storage Disorders Research Sphingolipid Metabolism and Signaling

Publication details

Journal / source
Nature Cell Biology
Publisher
Springer Science and Business Media LLC
Volume
28
Issue
3
Pages
492–506
Publication date
12 February 2026
Language
EN