Aberrant amino acid-sensing promotes immunotherapy resistance via the inflammatory cytokine–ZBTB5–mTORC1 axis

Nature Cell Biology 2026

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Authors: Junyu Xiang, Tao Wang, Shuoran Tian, J. Li, Mengyun Luo, Y Wang, Aibei Du, Xu Chen, Fanxuan Tian, Lei Wang, Yongchao Zhang, Mengyi Han
+14 more Wenqing Hou, Xing Wang, Tao Hou, Qin Liu, D. Chen, Liangzhi Wen, Zhongyi Qin, Xianfeng Li, Cong Jiang, Qiaoqiao Zhang, Pengda Liu, Xiuwu Bian, Wenyi Wei, Bin Wang
DOI: 10.1038/s41556-026-01926-8
Cited by: 2
References: 67

Fields of Study & Subjects

PI3K/AKT/mTOR signaling in cancer Cancer Hypoxia and Metabolism Cancer Research and Treatments

Publication details

Journal / source
Nature Cell Biology
Publisher
Springer Science and Business Media LLC
Volume
28
Issue
5
Pages
1000–1014
Publication date
3 April 2026
Language
EN