Amino acid-derived ionizable lipids enable inhaled base editing for therapeutic gene correction in the lung

Nature Materials 2026

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Authors: Fanglin Gong, Yan Xu, Jingan Chen, Shun Zhang, Songtao Dong, Lauren Healy, Breanna Seto, Muye Zhou, Rick Xing Ze Lu, Gen Li, Tyler Thomson, Yinghua Tang
+11 more Z Chen, Krista Antonio, Andrew Varley, D Chen, Craig A. Hodges, Amy P. Wong, Jim Hu, Basil P. Hubbard, John F. Engelhardt, Ziying Yan, Bowen Li
DOI: 10.1038/s41563-026-02555-0
Cited by: 5
References: 79

Fields of Study & Subjects

RNA Interference and Gene Delivery CRISPR and Genetic Engineering RNA and protein synthesis mechanisms

Publication details

Journal / source
Nature Materials
Publisher
Springer Science and Business Media LLC
Publication date
1 April 2026
Language
EN