Phage-associated Cas12p nucleases require binding to bacterial thioredoxin for activation and cleavage of target DNA

Nature Microbiology 2026

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Authors: Zhipeng Wang, Yujue Wang, Hui Gao, Jiani Dai, Na Tang, Yannan Wang, Quanjiang Ji
DOI: 10.1038/s41564-025-02224-z
Cited by: 2
References: 89

Fields of Study & Subjects

CRISPR and Genetic Engineering Bacterial Genetics and Biotechnology Bacteriophages and microbial interactions

Publication details

Journal / source
Nature Microbiology
Publisher
Springer Science and Business Media LLC
Volume
11
Issue
1
Pages
81–93
Publication date
2 January 2026
Language
EN