Safety considerations for cereblon-recruiting targeted protein degraders

Nature Reviews Drug Discovery 2026

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Authors: Helen Garside, Amy Aslamkhan, Danette L. Daniels, Kaushik Datta, Mikael E. Pedersen, Renee R. Hukkanen, Lyn H. Jones, N Ketter, Tejas S. Lahoti, Lise I. Loberg, Davorka Messmer, Raegan O'Lone
+11 more Timothy Pastoor, Mira Pavkovic, Lucilia Pereira Mouriès, Zoran Ranković, Aishwarya Rengarajan, Neil Vargesson, Axel Vicart, Ronald L. Wange, Gina Yanochko-Hoffman, Ruth Roberts, James D. Sidaway
DOI: 10.1038/s41573-026-01426-2
Cited by: 3
References: 163

Fields of Study & Subjects

Protein Degradation and Inhibitors Click Chemistry and Applications CAR-T cell therapy research

Publication details

Journal / source
Nature Reviews Drug Discovery
Publisher
Springer Science and Business Media LLC
Volume
25
Issue
8
Pages
648–662
Publication date
20 April 2026
Language
EN