De novo design of GPCR exoframe modulators

Nature 2026

View at publisher
Authors: Shizhuo Cheng, Jia Guo, Yunli Zhou, Xumei Luo, Gufang Zhang, Ya-zhi Zhang, Yixin Yang, Yixin Yang, Jiannan Xie, Ping Xu, Dan-Dan Shen, ShaoKun Zang
+5 more Huicui Yang, Xuechu Zhen, Min Zhang, Yan Zhang, Yan Zhang
DOI: 10.1038/s41586-025-09957-1
Cited by: 7
References: 70

Fields of Study & Subjects

Receptor Mechanisms and Signaling Nicotinic Acetylcholine Receptors Study Phosphodiesterase function and regulation

Publication details

Journal / source
Nature
Publisher
Springer Science and Business Media LLC
Volume
651
Issue
8104
Pages
242–250
Publication date
16 February 2026
Language
EN