Psychedelics elicit their effects by 5-HT2A receptor-mediated Gi signalling

Nature 2026

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Authors: Zheng Xu, Hao Wang, Jingjing Yu, Yue Deng, Xinyu Tian, Rongjun Ni, Fan Xia, Lingyi Yang, Chanjuan Xu, Liting Zhang, Renxuan Luo, Peipei Chen
+24 more Xiaoyu Zhang, Yuxuan Liu, Jingyu Hou, Miyuan Zhang, Shasha Chen, Lantian Su, Hui Sun, Yixiao He, DanDan Chen, Xiaoting Chen, Zhuang Miao, Jie Xie, Xinlei Liu, Jie Zhao, Bowen Ke, Xuan Tian, Linan Zeng, Lingli Zhang, Xiangdong Tang, Shengyong Yang, Jianfeng Liu, X. Q. Wang, Wei Yan, Zhenhua Shao
DOI: 10.1038/s41586-025-10061-7
Cited by: 15
References: 65

Fields of Study & Subjects

Psychedelics and Drug Studies Nicotinic Acetylcholine Receptors Study Forensic Toxicology and Drug Analysis

Publication details

Journal / source
Nature
Publisher
Springer Science and Business Media LLC
Volume
651
Issue
8106
Pages
829–837
Publication date
28 January 2026
Language
EN