Proteasome-guided haem signalling axis contributes to T cell exhaustion

Nature 2026

View at publisher
Authors: Yingxi Xu, Yangtao Shangguan, Yu‐Ming Chuang, Tzu-Hsuan Chang, Wenbing Liu, Jhan-Jie Peng, Josep Garnica, Leling Xie, Pei‐Chun Hsueh, Mei-Chun Lin, Yihao Wang, Karina Lôbo Hajdu
+19 more Y. Wu, Maryam Akrami, Chen Wang, Anna Kohl, Alfred Zippelius, Qi Wei, Min Wang, Bugi Ratno Budiarto, Shih‐Yu Chen, Zhengtao Xiao, Panagiota Vardaka, Rahul Roychoudhuri, Zhiliang Bai, Rong Fan, Santiago J. Carmona, Yi-Ru Yu, Christoph Scheiermann, Jianxiang Wang, Ping-Chih Ho
DOI: 10.1038/s41586-026-10250-y
Cited by: 7
References: 83

Fields of Study & Subjects

CAR-T cell therapy research Ubiquitin and proteasome pathways Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Nature
Publisher
Springer Science and Business Media LLC
Volume
653
Issue
8114
Pages
548–557
Publication date
18 March 2026
Language
EN