Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

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Authors: Sanjeev S. Ranade, Feiya Li, Sean Whalen, Angelo Pelonero, Lin Ye, Yu Huang, Abigail Brand, Tomohiro Nishino, Rahul Mital, Ryan M. Boileau, Frances L. Koback, Arun Padmanabhan
+11 more Victoria Yu, Bastien Cimarosti, Diana Presas-Ramos, Alexander F. Merriman, Langley Grace Wallace, Annie B. Nguyen, Nikolaos Poulis, Mauro W. Costa, Casey A. Gifford, Katherine S. Pollard, Deepak Srivastava
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Abstract

During the proof stage of this paper, the description of the statistical method in the legend for Fig. 4e was incorrectly edited to “Two-sided Fisher’s exact test, p value reported on graph.” The correct statistical method used, as stated during the peer review process, was a directional score test for equality of proportions using a Chi-square approximation. We have now corrected this in the figure legend to state “One-sided Chi-squared analysis, p value reported on graph.” We also note that the p value for comparison of WT to Tg animals is 0.036, not 0.032 as originally presented in the figure. The conclusions of this panel are unchanged.

Fields of Study & Subjects

Congenital heart defects research Pluripotent Stem Cells Research Down syndrome and intellectual disability research

Publication details

Journal / source
Nature
Volume
651
Issue
8105
Pages
E10–E10
Publication date
26 February 2026
Language
EN