Targeting cancer-specific mutations with RNA-triggered chromatin shredding

Nature 2026 Open access

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Authors: Jingkun Zeng, Zhiyuan Cheng, Huadong Chen, Zhaojun Wang, Jared Thompson, Kadin T. Crosby, Hesong Han, Arushi Singhal, Wayne Ngo, Chenglong Xia, Daniel Rosas-Rivera, Zeyuan Zhang
+13 more Min Hyung Kang, Ying Mao, Morgan E. Diolaiti, Giselle Lee, John F.X. Diffley, Yixuan Song, Longhui Qiu, Nathan M. Krah, Niren Murthy, Ryan N. Jackson, Yang Liu, Alan Ashworth, Jennifer A. Doudna
DOI: 10.1038/s41586-026-10738-7
Cited by: 6
References: 58

Fields of Study & Subjects

CRISPR and Genetic Engineering RNA regulation and disease RNA Interference and Gene Delivery

Publication details

Journal / source
Nature
Publisher
Springer Science and Business Media LLC
Volume
656
Issue
8126
Pages
199–206
Publication date
8 June 2026
Language
EN