In vivo genome-wide CRISPR screens of human T cells in solid tumours

Nature 2026

View at publisher
Authors: Qi Liu, Peixin Amy Chen, Esha Urs, Shimin Zhang, Maya M. Arce, Charlotte H. Wang, Jun Yan, Vinh Q. Nguyen, Zhongmei Li, Jin Seo, Nupura Kale, Fanglue Peng
+21 more Yikai Luo, Laine Goudy, Taylor N. LaFlam, Haixia Zhong, Chandrima Modak, Emma Dann, Jae Hyung Jung, Amanda Kirane, Allison Betof Warner, Boi Bryant Quach, Zinaida Good, Brian R. Shy, Eric Shifrut, Sagar P. Bapat, Greg M. Allen, Justin Eyquem, Katherine Cynthia Fuh, Stacie E. Dodgson, Brian J. Laidlaw, Alexander Marson, Julia C. Carnevale
DOI: 10.1038/s41586-026-10906-9
Cited by: 1
References: 60

Fields of Study & Subjects

CAR-T cell therapy research CRISPR and Genetic Engineering Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Nature
Publisher
Springer Science and Business Media LLC
Volume
658
Issue
8135
Pages
496-507
Publication date
12 August 2026
Language
EN