In vivo endosomal escape assay identifies mechanisms for efficient hepatic LNP delivery

Nature Biotechnology 2026 Open access

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Authors: Antony Jozić, C. Roux, Jeonghwan Kim, Mathieu Berchel, Deepak Kumar Sahel, Emily Bodi, Michelle Palumbo, Aishwarya Vasudevan, Namratha Turuvekere Vittala Murthy, Yulia Eygeris, Milan Gautam, Elissa Bloom
+3 more Anthony Barnes, Paul-Alain Jaffrès, Gaurav Sahay
DOI: 10.1038/s41587-026-03022-6
Cited by: 12
References: 66

Fields of Study & Subjects

RNA Interference and Gene Delivery Cellular transport and secretion Endoplasmic Reticulum Stress and Disease

Publication details

Journal / source
Nature Biotechnology
Publisher
Springer Science and Business Media LLC
Publication date
11 March 2026
Language
EN