Retargeted serine integrases for one-step, precise integration of large DNA sequences in human cells

Nature Biotechnology 2026

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Authors: Friedrich Fauser, Sebastian Arangundy‐Franklin, Jessica E. Davis, Lifeng Liu, Nicola Schmidt, Luis Rodriguez, Danny F. Xia, Nga Nguyen, Yuanyue Zhou, Nicholas A. Scarlott, Lynn Truong, Rakshaa Mureli
+18 more Irene S. Tan, Satria Sajuthi, Sarah J. Hinkley, Bhakti N. Kadam, Stephen C.-T. Lam, Bryan Bourgeois, Emily Tait, Mohammad Qasim, Vishvesha Vaidya, Adeline Chen, Andrew Nguyen, Yuri R. Bendaña, David A. Shivak, Patrick Li, Andreas Reik, David E. Paschon, Gregory D. Davis, Jeffrey C. Miller
DOI: 10.1038/s41587-026-03186-1
Cited by: 6
References: 68

Fields of Study & Subjects

CRISPR and Genetic Engineering Biochemical and Molecular Research HIV/AIDS drug development and treatment

Publication details

Journal / source
Nature Biotechnology
Publisher
Springer Science and Business Media LLC
Publication date
29 June 2026
Language
EN