Single-nucleus multimodal spatial transcriptomics reveals spatial colocalization of neoantigen-expressing tumor cells and cognate T cells

Nature Biotechnology 2026

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Authors: Adi Nagler, Amit Sud, Jack Y. Ghannam, Lucas Pomerance, Camila Robles-Oteíza, Alexander B. Afeyan, Jackson A. Weir, Andrew J. C. Russell, Wesley S. Lu, McKayla Van Orden, Andrea Sonnenholzner, Giovanni J. Marrero
+21 more Qiyu Gong, Vipin Kumar, Kun Huang, Chloe Tu, Emma Lin, Bohoon Shim, Gabriel R. De Oliveira, MacLean Sellars, Charles H. Yoon, David A. Reardon, Toni K. Choueiri, Lars R. Olsen, Sabina Signoretti, Patrick Alexander Ott, David A. Braun, Giacomo Oliveira, Shuqiang Li, Kenneth J. Livak, Nir Hacohen, Fei Chen, Catherine J. Wu
DOI: 10.1038/s41587-026-03194-1
Cited by: 1
References: 94

Fields of Study & Subjects

Single-cell and spatial transcriptomics Advanced biosensing and bioanalysis techniques Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Nature Biotechnology
Publisher
Springer Science and Business Media LLC
Publication date
22 July 2026
Language
EN