Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Nature Biotechnology 2026 Open access

Read full text
Authors: Hyuncheol Jung, Pascal Devant, Carter Ching, Mineto Ota, Emma Dann, Ronghui Zhu, Chandrima Modak, Ana Vasquez-Ibarra, Jennifer Hamilton, Zachary Steinhart, Wayne Ngo, Luis Sandoval
+18 more Jae Hyung Jung, Jae Hyun J. Lee, Da Xu, Meirui An, Esha Urs, Peixin Amy Chen, Vincent Allain, Takuya Tada, Luke A. Gilbert, Brian R. Shy, Jonathan K. Pritchard, James K. Nuñez, Nathaniel R. Landau, David Liu, Justin Eyquem, Jennifer A. Doudna, Alexander Marson, Julia Carnevale
DOI: 10.1038/s41587-026-03258-2
Cited by: 4
References: 72

Fields of Study & Subjects

CRISPR and Genetic Engineering interferon and immune responses RNA regulation and disease

Publication details

Journal / source
Nature Biotechnology
Publisher
Springer Science and Business Media LLC
Publication date
17 August 2026
Language
EN