Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry

Nature Genetics 2026 Open access

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Authors: James L. Li, Haoyu Zhang, Xiaoyu Wang, Guochong Jia, Julian McClellan, Wenji Guo, Yijia Sun, Peter N. Fiorica, Stefan Ambs, Mollie E. Barnard, Yu Chen, Montserrat Garcia-Closas
+43 more Jian Gu, Jennifer J. Hu, Esther M. John, Katherine L. Nathanson, Barbara Nemesure, Tuya Pal, Xiao-Ou Shu, Michael R. Sisak & Eric Tucker | The Associated Press, Maureen Sanderson, Dale P. Sandler, Melissa A. Troester, Song Yao, Jirong Long, Thomas U. Ahearn, Abenaa M. Brewster, Adeyinka G. Falusi, Peter Kraft, Anselm Hennis, Timothy Makumbi, Berthe SE Mapoko, Katie M. O’Brien, Oladosu Ojengbede, Andrew F. Olshan, Sonya Reid, Gary Zirpoli, Qiuyin Cai, Eboneé N. Butler, Maosheng Huang, John Obafunwa, Clarice R. Weinberg, Christine Ambrosone, Jie Ping, Ran Tao, Bingshan Li, Xingyi Guo, Guimin Gao, David V. Conti, Nilanjan Chatterjee, Julie R. Palmer, Olufunmilayo I. Olopade, Wei Zheng, Christopher A. Haiman, Dezheng Huo
DOI: 10.1038/s41588-026-02501-5
Cited by: 5
References: 48

Fields of Study & Subjects

BRCA gene mutations in cancer Breast Cancer Treatment Studies Global Cancer Incidence and Screening

Publication details

Journal / source
Nature Genetics
Publisher
Springer Science and Business Media LLC
Volume
58
Issue
3
Pages
560–569
Publication date
2 February 2026
Language
EN