H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs

Nature Genetics 2026 Open access

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Authors: Brian Krug, Bo Hu, Haifeng Chen, Claudia Negrón-Lomas, Xiao Chen, Ahmed El Mouatani, Kristjan H. Gretarsson, Adam Ptack, Shriya Deshmukh, Nisha Kabir, Wajih Jawhar, Augusto Faria Andrade
+25 more Elias Jabbour, Ashot S. Harutyunyan, Xinrui Wang, Robert Taylor, John J. Y. Lee, Maud Hulswit, Damien Faury, Caterina Russo, Xinjing Xu, Jiahan Yang, Audrey Baguette, Nathan Dahl, Alexander G. Weil, Benjamin Ellezam, Rola Dali, Mathieu Blanchette, Khadija Wilson, Benjamin A. García, Rajesh K. Soni, Marco Gallo, Michael D. Taylor, Claudia L. Kleinman, Jacek Majewski, Nada Jabado, Chao Lü
DOI: 10.1038/s41588-026-02586-y
Cited by: 5
References: 119

Fields of Study & Subjects

Epigenetics and DNA Methylation Glioma Diagnosis and Treatment Genomics and Chromatin Dynamics

Publication details

Journal / source
Nature Genetics
Publisher
Springer Science and Business Media LLC
Volume
58
Issue
6
Pages
1368–1382
Publication date
18 May 2026
Language
EN