Targeting thymine DNA glycosylase induces synthetic lethality in p53-deficient cancers

Nature Chemical Biology 2026

View at publisher
Authors: Jiaxin Zhou, Zhenyu Shao, Lin Zhang, Lin Zhang, Jian-Nan Guo, Meng Wang, Qin Xu, Yi-Qin Wang, Qing Xu, Dan Zhou, Sheng-xiang Ren, Zhi-Hao Lu
+12 more Zhi-Hao Lu, Guo-Zheng Pang, Yao Cao, Yi-Lin Liu, Bin Zhou, Hong-Bin Ji, Yihan Chen, Guo-Liang Xu, Guo-Liang Xu, Liang Zhang, Liang Zhang, Yarui Du
DOI: 10.1038/s41589-025-02100-1
Cited by: 3
References: 74

Fields of Study & Subjects

Genomics and Chromatin Dynamics interferon and immune responses RNA Research and Splicing

Publication details

Journal / source
Nature Chemical Biology
Publisher
Springer Science and Business Media LLC
Volume
22
Issue
7
Pages
1109–1119
Publication date
22 January 2026
Language
EN