Unique gluing effect of ASXL1 K351 monoubiquitination stimulates the PR-DUB activity

Nature Chemical Biology 2026

View at publisher
Authors: Tianyi Zhang, Jiqing Zheng, Zebing Tong, Zhiheng Deng, Zaozhen He, Xiangwei Wu, Miao Wang, Yunxiang Du, Ziyu Xu, Shixian Tao, Shizhang Wan, Xiaolin Tian
+4 more Haiteng Deng, Man Pan, Huasong Ai, Lei Liu
DOI: 10.1038/s41589-025-02126-5
Cited by: 3
References: 57

Fields of Study & Subjects

Ubiquitin and proteasome pathways Protein Degradation and Inhibitors Autophagy in Disease and Therapy

Publication details

Journal / source
Nature Chemical Biology
Publisher
Springer Science and Business Media LLC
Volume
22
Issue
8
Pages
1311–1319
Publication date
9 January 2026
Language
EN