Autopalmitoylation of IDH1-R132H regulates its neomorphic activity in cancer cells

Nature Chemical Biology 2026

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Authors: Lu Hu, Jinyu Lin, Liping Sun, Alison M. Berezuk, Katharine S. Tuttle, Xing Quan Zhu, Hyuk‐Soo Seo, Sirano Dhe-Paganon, Pan Li, Yang Sun, Lisheng Ni, Jianan Zhang
+9 more Dazhi Tan, Hiroaki Wakimoto, Daniel P. Cahill, Xiaochen Bai, Xuelian Luo, John M. Asara, Sriram Subramaniam, Yibing Shan, Xu Wu
DOI: 10.1038/s41589-025-02131-8
Cited by: 1
References: 62

Fields of Study & Subjects

Cancer Lipids and Metabolism Hypoxia Glioma Diagnosis and Treatment

Publication details

Journal / source
Nature Chemical Biology
Publisher
Springer Science and Business Media LLC
Volume
22
Issue
7
Pages
1087–1098
Publication date
13 January 2026
Language
EN