Abasic CRISPR RNAs inherently harness fidelity of SpCas9 for genome editing

Nature Chemical Biology 2026

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Authors: Dowoon Gu, Geun-Woo D. Kim, Mingyo Park, Alexander Doh Park, Hye-Sook Lee, Sangkyeong Eom, Haban Weon, Jongyeun Park, Jung Lee, Seung Hyun Ahn, H E Oh, Jaeyoung Kim
+5 more S. Kim, Nakbeom Seong, Junho K. Hur, Eun-Sook Jang, Sung Wook Chi
DOI: 10.1038/s41589-026-02139-8
Cited by: 2
References: 79

Fields of Study & Subjects

CRISPR and Genetic Engineering RNA regulation and disease interferon and immune responses

Publication details

Journal / source
Nature Chemical Biology
Publisher
Springer Science and Business Media LLC
Publication date
5 February 2026
Language
EN