An evolution-conserved allosteric network in human tubulin governs paclitaxel efficacy

Nature Chemical Biology 2026

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Authors: JINGYI LUO, Chen Jing Khoo, W Chen, Zheng Liu, Boxuan Li, Wei Sin Lau, Xiang Li, Shih-Chieh Ti
DOI: 10.1038/s41589-026-02204-2
Cited by: 4
References: 58

Fields of Study & Subjects

Microtubule and mitosis dynamics Cancer Treatment and Pharmacology 14-3-3 protein interactions

Publication details

Journal / source
Nature Chemical Biology
Publisher
Springer Science and Business Media LLC
Publication date
15 April 2026
Language
EN