PARP inhibition generates enhanced CD8+ central memory T cells by transcriptional and metabolic reprogramming

Nature Immunology 2026

View at publisher
Authors: Waël Traboulsi, Pankaj Gaur, Subhadip Kundu, Zainab Ramlaoui, Christopher Priestley-Milianta, Aishwariya Srikala Iyengar, Nour Shobaki, Dareen Sarhan, Min-Jung Lee, Jung-Min Lee, George N. Pavlakis, Mikayel Mkrtichyan
+5 more Viia Valge-Archer, Simon T. Barry, Vivek Verma, Seema Gupta, Samir N. Khleif
DOI: 10.1038/s41590-025-02383-5
Cited by: 5
References: 49

Fields of Study & Subjects

PARP inhibition in cancer therapy CAR-T cell therapy research Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Nature Immunology
Publisher
Springer Science and Business Media LLC
Volume
27
Issue
2
Pages
189–199
Publication date
12 January 2026
Language
EN