Purine salvage pathway protects CD8+ T cells from metabolic stress

Nature Immunology 2026

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Authors: Masaki Tajima, He Hao, Baihao Zhang, Yuta Matsuoka, Kazuhiro Sonomura, Koshi Imami, Yosuke Isobe, Rae Maeda, Yu‐Hsien Lin, Akihiro Shimba, Ryoma Kato, Pedro Henrique Costa Cruz
+18 more Sayaka Washizu, Yosuke Ikejiri, Akiyo Morinibu, Clive Steven Barker, Jun Seita, Yibo Wu, Satomi Ito, Seiko Narushima, Rei Nakano, Mikako Maruya, Wakana Kobayashi, Sai Shanmukha Priya Narayanan, Jumana Shaheen, Hiroyuki Neyama, Ken‐ichi Yamada, Makoto Arita, Yuki Sugiura, Sidonia Fagarasan
DOI: 10.1038/s41590-026-02491-w
Cited by: 1
References: 54

Fields of Study & Subjects

Ferroptosis and cancer prognosis Immune cells in cancer Gut microbiota and health

Publication details

Journal / source
Nature Immunology
Publisher
Springer Science and Business Media LLC
Volume
27
Issue
5
Pages
1026–1038
Publication date
13 April 2026
Language
EN