Fractional flow reserve-guided percutaneous coronary intervention versus medical therapy for stable coronary artery disease: long-term results of the FAME 2 trial

Nature Medicine 2026

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Authors: Carlos Collet, Thabo Mahendiran, William F. Fearon, Takuya Mizukami, Daniel Munhoz, Nico H J Pijls, Pim A. L. Tonino, Emanuele Barbato, Zsolt Piróth, Miodrag Srećković, Holger Thiele, Mohamed El Farissi
+18 more Nils Witt, Gilles Rioufol, Petr Kala, Thomas Engstrøm, Kreton Mavromatis, Ole Fröbert, Peter VerLee, S Brunner, Martin Mates, Nikola Jagić, Gianluca Campo, Sofie Pardaens, Kazumasa Ikeda, Tiago Veiga Pereira, Bruno R. da Costa, Stephane Fournier, Bernard De Bruyne, Peter Jüni
DOI: 10.1038/s41591-025-04132-5
Cited by: 12
References: 17

Fields of Study & Subjects

Coronary Interventions and Diagnostics Cardiac Imaging and Diagnostics Acute Myocardial Infarction Research

Publication details

Journal / source
Nature Medicine
Publisher
Springer Science and Business Media LLC
Volume
32
Issue
1
Pages
318–324
Publication date
1 January 2026
Language
EN