Amyloid-β-driven glymphatic dysfunction in Alzheimer’s disease model mice is driven by Ca2+-mediated increases in astrocytic cholesterol

Nature Neuroscience 2026

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Authors: Zhan Zhang, Shaojian Li, Liang Xu, Songhua Xiao, Yi Li, Jialin Huang, Jingxuan Huang, You Zuo, Wenjie Wen, Qingyuan Dai, Chuan Xiao, X P Zhang
+11 more Jiongxue Chen, 邓富银, Jinbiao Li, Yongteng Xu, Xia Hu, Zhenhong Deng, Yuan Luo, Xiaoru Xie, Xiaojing Ye, Wei‐Jye Lin, Yamei Tang
DOI: 10.1038/s41593-026-02261-9
Cited by: 6
References: 72

Fields of Study & Subjects

Cerebrospinal fluid and hydrocephalus Spinal Dysraphism and Malformations Alzheimer's disease research and treatments

Publication details

Journal / source
Nature Neuroscience
Publisher
Springer Science and Business Media LLC
Volume
29
Issue
6
Pages
1369–1385
Publication date
15 April 2026
Language
EN