Neuroproteasomes regulate endogenous tau paired helical filament formation in an APOE genotype- and age-dependent manner

Nature Neuroscience 2026 Open access

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Authors: Victoria Paradise, Kalin D. Konrad-Vicario, Chi Nguyen, Nyle A Sharif, X Wang, Rijuta D. Mukim, Malavika Sabu, Bianca T. Corjuc, J Bafia, Jack Fu, Gabriella C. Maldonado, Michael Strickland
+6 more Sarah Grauman, Helen Figueroa, Bradley T. Hyman, David M. Holtzman, Tal Nuriel, Kapil V. Ramachandran
DOI: 10.1038/s41593-026-02297-x
Cited by: 3
References: 58

Fields of Study & Subjects

Alzheimer's disease research and treatments Cellular transport and secretion Microtubule and mitosis dynamics

Publication details

Journal / source
Nature Neuroscience
Publisher
Springer Science and Business Media LLC
Volume
29
Issue
9
Pages
2151–2163
Publication date
29 May 2026
Language
EN