Redox-driven ADAR1 activation promotes Okazaki fragment maturation and DNA replication integrity

Nature Structural & Molecular Biology 2026

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Authors: Bin Chen, Guangchao Sun, Jake A. Kloeber, Huaping Xiao, Yaobin Ouyang, Fei Zhao, Y. Li, Shilin Xu, Sonja Dragojevic, Zheming Wu, Shouhai Zhu, Yiqun Han
+12 more Ping Yin, Xinyi Tu, Hongran Qin, X. Edward Zhou, Kuntian Luo, Kevin L. Peterson, Jinzhou Huang, Taro Hitosugi, Haiming Dai, Min Deng, Robert W. Mutter, Zhenkun Lou
DOI: 10.1038/s41594-025-01736-w
Cited by: 1
References: 47

Fields of Study & Subjects

RNA regulation and disease RNA and protein synthesis mechanisms RNA modifications and cancer

Publication details

Journal / source
Nature Structural & Molecular Biology
Publisher
Springer Science and Business Media LLC
Volume
33
Issue
2
Pages
293–303
Publication date
8 January 2026
Language
EN