Resolution of R-loops and transcription–replication conflicts by SETX–BRCA1–BARD1 complex

Nature Structural & Molecular Biology 2026 Open access

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Authors: Arijit Dutta, Jae-Hoon Ji, Shahrez Syed, Qingming Fang, Pramiti Mukhopadhyay, Hanzhou Wang, Eva Loranc, Daisy Medina, Shahad Abdulsahib, Shuo Zhou, Miriam Tovar, Jeff Wang
+27 more Jane M Benoit, Fengshan Liang, Nozomi Tomimatsu, Julius O. Nyalwidhe, Eloïse Dray, Amy Verway-Cohen, Drew T. McDonald, Bárbara de la Peña Avalos, Wenjing Li, Ane Olazabal Herrero, O’Taveon Fitzgerald, Alexander B. Taylor, Youngho Kwon, O. John Semmes, Miaw-Sheue Tsai, Manjeet Rao, Robert Hromas, Sandeep Burma, Yidong Chen, Alexander V. Mazin, Elizabeth V. Wasmuth, Shaun K. Olsen, Daohong Zhou, Alexander J. R. Bishop, Weixing Zhao, Gary M. Kupfer, Patrick Sung
DOI: 10.1038/s41594-026-01778-8
Cited by: 5
References: 72

Fields of Study & Subjects

DNA Repair Mechanisms BRCA gene mutations in cancer Genomics and Chromatin Dynamics

Publication details

Journal / source
Nature Structural & Molecular Biology
Publisher
Springer Science and Business Media LLC
Volume
33
Issue
4
Pages
615–630
Publication date
31 March 2026
Language
EN