Hypervariable loop profiling decodes sequence determinants of antibody stability

Nature Structural & Molecular Biology 2026

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Authors: Yue Wan, Jiahao Liang, Yile Dai, Karthik Srinivasan, Christian B. Billesbølle, Ju-Fen Zhu, Jung-Eun Shin, Steffanie Paul, D S Marks, Yun S Song, Benjamin R. Myers, Antoine Koehl
+1 more Aashish Manglik
DOI: 10.1038/s41594-026-01804-9
Cited by: 1
References: 88

Fields of Study & Subjects

Monoclonal and Polyclonal Antibodies Research vaccines and immunoinformatics approaches Biochemical and Structural Characterization

Publication details

Journal / source
Nature Structural & Molecular Biology
Publisher
Springer Science and Business Media LLC
Volume
33
Issue
6
Pages
998–1010
Publication date
30 April 2026
Language
EN