Retraction Note: The effect of Ganoderma lucidum polysaccharide extract on sensitizing prostate cancer cells to flutamide and docetaxel: an in vitro study

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Authors: Ramin Rahimnia, Mohmammad Reza Akbari, Alimohammad Fakhr Yasseri, Diana Taheri, Akram Mirzaei, Helia Azodian Ghajar, Parmida Dehghanpoor Farashah, Leila Zareian Baghdadabad, Seyed Mohammad Kazem Aghamir
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References: 2

Abstract

After publication, concerns were raised regarding the data presented in the Figures, specifically: Fig. 1 PC3 10um Doc appears to overlap with Fig. 1e of 1 ; Fig. 1 LNCap 5um Doc and Flu-Doc images appear to overlap; Fig. 3A and B share similar features, and C and D appear highly similar; Fig. 4A LNCap 5µM Doc and LNCap Flu, Doc & Ganoderma lucidum plots appear highly similar; Fig. 4A PC3 10µM Doc and PC3 Doc + Ganoderma lucidum plots appear highly similar. A number of flow cytometry plots in Fig. 4A appear higly similar to those in Figs. 3 and 4 of 1 and Fig. 5 of 2 , representing different cell lines and treatments; Fig. 6A 3 combination and 6B Flu+Doc images appear highly similar; Fig. 6A 5µM Doc and 6B 10µM Doc images appear to overlap; Fig. 6A 20µM GLP and 6B Doc+GLP images appear to overlap; Fig. 6A Flu+GLP and 6B Control-0 images appear to overlap with rotation; Fig. 7 20µM Flu, Flu+GLP and 3 combination images appear to originate from the same sample; Fig. 7 10µM Doc and 30µM GLP appear highly similar (with different brightness and contrast).

Fields of Study & Subjects

Fungal Biology and Applications Polysaccharides and Plant Cell Walls Antioxidants Aging Portulaca oleracea

Publication details

Journal / source
Scientific Reports
Volume
16
Issue
1
Pages
427–427
Publication date
6 January 2026
Language
EN