Retraction Note: Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer

Scientific Reports 2026 Open access

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Authors: Hamid Jamialahmadi, Seyedeh Elnaz Nazari, Hamid Tanzadehpanah, Ehsan Saburi, Fereshteh Asgharzadeh, Fatemeh Khojasteh‐Leylakoohi, Maryam Alaei, Mahdi Mirahmadi, Fatemeh Babaei, Seyedeh Zahra Asghari, Saeide Mansouri, Ghazaleh Khalili‐Tanha
+6 more Mina Maftooh, Hamid Fiuji, Seyed Mahdi Hassanian, Gordon A. Ferns, Majid Khazaei, Amir Avan
DOI: 10.1038/s41598-025-34893-5
Cited by: 0

Abstract

After publication, concerns has been raised about the data and the inconsistencies between its presentation and the description in the methods section, as well as the conduct of the animal experiments. The Editors requested explanation and the raw data underlying the paper. Only some of the data was provided and did not contain metadata to allow verification of its veracity, nor address the main concerns. Specifically:

Fields of Study & Subjects

TGF-β signaling in diseases Colorectal Cancer Treatments and Studies Pancreatic and Hepatic Oncology Research

Publication details

Journal / source
Scientific Reports
Volume
16
Issue
1
Pages
2194–2194
Publication date
19 January 2026
Language
EN