Retraction Note: A novel chalcone derivative S17 induces apoptosis through ROS dependent DR5 up-regulation in gastric cancer cells

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Authors: Saiyang Zhang, Tingyu Li, Li Zhang, Xiangyu Wang, Hangqi Dong, Lili Li, Dongjun Fu, YongChun Li, Xiaolin Zi, Hong-Min Liu, Yanbing Zhang, Hongde Xu
+1 more Cheng-Yun Jin
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Abstract

After publication, concerns were raised regarding the data presented. Specifically, Figure 2D panel 1 and panel 3 appear to overlap. The Editors requested the original data underlying the study, but the Authors were not able to provide it. Additional concern was also identified in that the cell lines used in the study were contaminated with HeLa cells, and therefore not suitable model of a gastric cancer. The Editors therefore no longer have confidence in the data presented in the Article.

Fields of Study & Subjects

Synthesis and biological activity Cell death mechanisms and regulation Flavonoids in Medical Research

Publication details

Journal / source
Scientific Reports
Volume
16
Issue
1
Pages
2195–2195
Publication date
19 January 2026
Language
EN