Association between monocyte-to-lymphocyte ratio and mortality in patients with acute pancreatitis requiring intensive care unit admission: a retrospective cohort study and predictive model establishment based on machine learning

Jie Yang; Caitao Dong; Mengmeng Guo; Jingdi Chen; Handong Zou; Hang Gao; Jing Xu; Yang Liu; Wei Wu; Shuai Yang

doi:10.1038/s41598-026-37791-6

Association between monocyte-to-lymphocyte ratio and mortality in patients with acute pancreatitis requiring intensive care unit admission: a retrospective cohort study and predictive model establishment based on machine learning

Scientific Reports 2026 Open access

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Authors: Jie Yang, Caitao Dong, Mengmeng Guo, Jingdi Chen, Handong Zou, Hang Gao, Jing Xu, Yang Liu, Wei Wu, Shuai Yang

DOI: 10.1038/s41598-026-37791-6

Cited by: 0

References: 27

Abstract

The purpose of this study was to evaluate the predictive value of monocyte-to-lymphocyte ratio (MLR) on the short-term (28 days) and long-term (365 days) mortality risk in patients with acute pancreatitis (AP) using multiple statistical and machine learning (ML) models. Studies selected 1,044 eligible AP patients from the MIMIC-IV database and divided them into four groups based on their MLR values (MLR

Fields of Study & Subjects

Pancreatitis Pathology and Treatment Sepsis Diagnosis and Treatment Inflammatory Biomarkers in Disease Prognosis

Publication details

Journal / source: Scientific Reports
Volume: 16
Issue: 1
Publication date: 15 February 2026
Language: EN

References 27