Correction: GRB2 promotes brain metastasis in HER2-positive breast cancer by regulating the Ras/MAPK pathway

Read full text
Authors: Hongyu Li, Yalin Zhang, Xiao Han, Bingyu Li, Dan Liu, Gang Sun
Cited by: 0

Abstract

The original version of this Article contained errors in Figure 2, where there was a duplication between the images for LV-HER2 and LV-HER2 + LV-sh-NC in panel (f). The original Figure 2 and accompanying legend appear below. Figure 2 Results of cell proliferation, apoptosis, migration, and invasion across cell Lines. ( A , B ) Expression levels of GRB2 and HER2.* denotes a P-value < 0.05. ( C , D ) Differences in cell proliferation and apoptosis across experimental groups. ( E ) Differences in cell migration and invasion capabilities.* denotes a P-value < 0.05.***denotes a P-value < 0.01. ( F ) Microscopic examination of transwell migration and invasion assays. Blue staining indicates migrated or invaded cells, with a higher cell number reflecting stronger migration or invasion capability. ( G ) Differential expression of proteins in the Ras/MAPK pathway by western blot. β-actin serves as the reference protein band, and the darkness of the target band indicates high expression of the target protein in this sample. Full size image

Fields of Study & Subjects

Brain Metastases and Treatment HER2/EGFR in Cancer Research Protein Kinase Regulation and GTPase Signaling

Publication details

Journal / source
Scientific Reports
Volume
16
Issue
1
Pages
4729–4729
Publication date
3 February 2026
Language
EN