Digital infrared reflex testing and asynchronous teleconsultation for infant eye screening

Read full text
Authors: Elisabetta Racano, Chiara Spinelli, Giuseppina Sacco, Giorgia Benedetti, Federica Romanelli, Adele Compagnone, Marta Betta, Roberta Pasquini, Lorena Filippi, Lucia Pavanello, Giulia Malfatti, Riccardo Pertile
Cited by: 1
References: 18

Abstract

Early detection and documentation of anterior segment opacities in infants (aged 1–6 months) is limited by resource constraints and specialist availability. This study aimed to evaluate the usefulness of digital infrared reflex testing (IRRT) and to estimate the feasibility of asynchronous teleconsultation between primary care paediatricians and ophthalmologists for infant eye screening. From April 2024 to March 2025, 189 infants aged 1–6 months underwent both digital IRRT and standard red reflex testing (RRT) in primary care settings. Digital images and clinical data were evaluated using teleconsultation between paediatricians and ophthalmologists. The feasibility endpoints included the proportion of successful teleconsultations, user acceptability, and technical barriers. IRRT versus RRT diagnostic agreement and the IRRT inconclusive examination rate were also assessed. Teleconsultation was feasible in 84% of the cases. The principal barriers were operational issues (time and setting) and staff training needs. Digital IRRT had an inconclusive result rate of 5.3% and high agreement with RRT (AC1 = 0.994, 95% CI: 0.983–1.000). Digital IRRT combined with teleconsultation is a feasible and accurate approach for infant eye screening in primary care settings, supporting image documentation, integration into telemedicine workflows, and potential future AI applications.

Fields of Study & Subjects

Retinopathy of Prematurity Studies Intraocular Surgery and Lenses Ophthalmology and Visual Impairment Studies

Publication details

Journal / source
Scientific Reports
Publisher
Springer Science and Business Media LLC
Volume
16
Issue
1
Publication date
21 February 2026
Language
EN