Publisher Correction: Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model

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Authors: Kosuke Sakamoto, Shinji Nakamura, Toui Tsuchiya, Tsutomu Mitsuie, Yasuhiro Nakao, Yinmon Htun, Takayuki Yokota, Kota Inoue, Eri Inoue, Takayuki Wakabayashi, Aya Morimoto, Kosuke Koyano
+4 more Yukihiko Konishi, Takashi Iwase, Taiko Horii, Takashi Kusaka
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Abstract

The original Figures 1 – 2 and 4 – 5 and accompanying legends appear below. Fig. 1 Time course of changes in the physiological parameters MBP, HR and Lt. and Rt.CO before and within 6 h after HI insult in HI and HI-H2 groups. The shaded area indicates HI insult and dotted lines indicate baselines. Closed circle ( ● ), HI group (n = 10); open circle (〇), HI-H2 group (n = 7). #p < 0.05, ##p < 0.01, ####p < 0.0005 vs. baseline. Mean blood pressure (MBP) in HI ( A ) and HI-H2 ( B ) groups. Heart rate (HR) in HI ( C ) and HI-H2 ( D ) groups. Lt. and Rt. cardiac output (CO) in HI ( E , G ) and HI-H2 (F, H) groups. Value indicated mean (SD). Full size image Fig. 2 Comparison of MBP ( A ) and HR ( B ) in HI and HI-H 2 groups before and within 6 h after insult. The shaded area indicates HI insult and dotted lines indicate baselines. Closed circle ( ● ), HI group (n = 10); open circle (〇), HI-H2 group (n = 7). Value indicated mean (SD). Full size image Fig. 4 Comparison of RVOT VTI in HI and HI-H 2 groups before and within 6 h after insult. The shaded area indicates HI insult and dotted lines indicate baselines. Closed circle ( ● ), HI group ( n = 10); open circle (〇), HI-H 2 group ( n = 7). Value indicated mean (SD). Full size image Fig. 5 Comparison of serum cardiac troponin T levels in HI and HI-H2 groups before, at 3, 6 h after insultSerum cardiac troponin T concentrations were measured to assess myocardial injury. Due to sample availability, troponin T could be measured in 9 of 10 piglets in the HI group and 4 of 7 piglets in the HI–H₂ group.Troponin T levels at 6 h were significantly lower in the HI–H₂ group than in the HI group (HI: 0.16 ± 0.04 ng/mL; HI–H₂: 0.10 ± 0.02 ng/mL, p = 0.048). Closed circle ( ● ), HI group (n = 9); open circle (〇), HI-H 2 group (n = 4). Data are presented as mean ± SD. p < 0.05 vs. HI group. Full size image

Fields of Study & Subjects

Hydrogen's biological and therapeutic effects Neonatal and fetal brain pathology Biomedical and Chemical Research

Publication details

Journal / source
Scientific Reports
Volume
16
Issue
1
Publication date
6 March 2026
Language
EN