Start-to-end modelling of laser-plasma acceleration, beam transport and dose deposition of very high-energy electrons for radiotherapy

Scientific Reports 2026 Open access

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Authors: Rajakrishna Kalvala, Anton A. Golovanov, Arnaud Courvoisier, Tomer Friling, E. Kroupp, Lidan Grishko, Victor Malka
DOI: 10.1038/s41598-026-49116-8
Cited by: 0
References: 50

Abstract

The proposed radiotherapy using very high-energy electron (VHEE) beams generated by a laser-plasma accelerator has garnered significant interest due to its dose distribution capabilities and potential to address limitations of traditional photon-based radiotherapy. To explore the feasibility of such an approach, we develop a start-to-end simulation workflow to model VHEE radiotherapy from the electron source through the beamline to dose delivery in the target. The presented study uses the parameters of OONA, the commercial

Fields of Study & Subjects

Laser-Plasma Interactions and Diagnostics Laser-induced spectroscopy and plasma Plasma Diagnostics and Applications

Publication details

Journal / source
Scientific Reports
Publisher
Springer Science and Business Media LLC
Volume
16
Issue
1
Publication date
24 April 2026
Language
EN