A High-resolution metal–insulator–metal plasmonic biosensor with concentric ring resonators for carcinoembryonic antigen detection
Abstract
High-resolution optical sensors are vital for detecting subtle refractive index variations associated with biomolecular interactions, such as changes in carcinoembryonic antigen (CEA) concentration. This work presents a compact metal-insulator-metal (MIM) plasmonic sensor with two concentric ring resonators, numerically investigated using finite-difference time-domain simulations. Structural parameters are optimized to maximize field confinement and resonant mode coupling, yielding a sensitivity of 1035 nm/RIU, a resonance linewidth of 3.75 nm, and a figure of merit of 276 RIU⁻¹. The sensor demonstrates precise spectral shifts corresponding to minute refractive index changes linked to CEA, while the influence of surface-bound layers and fabrication tolerances is also assessed to ensure robustness under practical conditions. These results highlight the sensor's potential as a high-resolution, label-free platform for monitoring CEA in biological samples.
Fields of Study & Subjects
Plasmonic and Surface Plasmon Research
Metamaterials and Metasurfaces Applications
Advanced Fiber Optic Sensors
Publication details
- Journal / source
- Scientific Reports
- Publisher
- Springer Science and Business Media LLC
- Volume
- 16
- Issue
- 1
- Publication date
- 27 May 2026
- Language
- EN