The OurHealth Study: A digital genomic cohort for cardiometabolic risk mechanisms in US South Asians

npj Digital Medicine 2026 Open access

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Authors: Shriienidhie Ganesh, Romit Bhattacharya, Aarushi Bhatnagar, Rishi Madnani, Christine Russo, Sara Haidermota, Bhaavana Oruganty, Harshil Bhavsar, Priyansh Shah, Sarah Pitafi, Nishant Uppal, Namrata Sengupta
+14 more Kenneth M. Rice, Matthew P. Conomos, Ravi H. Dave, Abha Khandelwal, Aniruddh P. Patel, Kaavya Paruchuri, Yamini Levitsky, Sanchita Singal Parulkar, Rohan Khera, M. Gulati, Amit V. Khera, Whitney Hornsby, Latha P Palaniappan, Pradeep Natarajan
DOI: 10.1038/s41746-025-02335-1
Cited by: 0
References: 50

Abstract

South Asians experience disproportionately elevated cardiometabolic disease risk yet remain underrepresented in genomic research. The OurHealth Study builds a digital biobank of US South Asian adults, integrating remote surveys, mailed biospecimens for sequencing, and electronic health record sharing to identify genetic and non-genetic drivers of cardiometabolic disease. By pairing remote participation with culturally tailored outreach, OurHealth enhances accessibility, supports granular phenotyping, and addresses logistical barriers to genomic research inclusion.

Fields of Study & Subjects

Genetic Associations and Epidemiology Ethics in Clinical Research Health Environment Cognitive Aging

Publication details

Journal / source
npj Digital Medicine
Volume
9
Issue
1
Pages
151–151
Publication date
16 January 2026
Language
EN