Remote digital cognitive assessment for aging and dementia using the Oxford Cognitive Testing Portal OCTAL

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Authors: Sijia Zhao, Sofia Toniolo, Qian-Yuan Tang, Anna Scholcz, Akke Ganse-Dumrath, Claudia Gendarini, M. John Broulidakis, Sian Thompson, Sanjay Manohar, Masud Husain
Cited by: 3
References: 44

Abstract

The global rise in dementia necessitates scalable cognitive assessments that can evolve to serve both clinical and research applications. We present the Oxford Cognitive Testing Portal (OCTAL), a remote, browser-based platform providing performance metrics for memory, attention, visuospatial and executive function domains. Four validation studies (N = 1664) confirmed cross-cultural applicability, lifespan sensitivity and clinical utility. Task performance was equivalent in English- and Chinese-speaking younger adults and mapped domain-specific ageing trajectories in mid- to late-adulthood. In a memory-clinic cohort (N = 194), 5-minute OCTAL screen distinguished patients with Alzheimer's disease dementia from subjective cognitive decline (AUC = 0.92), matching a standard paper-based test, while a 20-minute subset surpassed this (AUC = 0.97; p = 0.04). Test-retest reliability was very good (ICC ≥ 0.79; N = 118). OCTAL enables remote assessment for large-scale research and screening, with an open, modular architecture that makes it a uniquely sustainable and evolvable tool for the research community.

Fields of Study & Subjects

Dementia and Cognitive Impairment Research Technology Use by Older Adults Cognitive Functions and Memory

Publication details

Journal / source
npj Digital Medicine
Publisher
Springer Science and Business Media LLC
Volume
9
Issue
1
Pages
162–162
Publication date
15 January 2026
Language
EN