Mechanisms of action for digital therapeutics
Abstract
Digital therapeutics (DTx) are increasingly established, yet their mechanisms of action (MoA) remain underexplored. This article defines and categorizes DTx MoA through a novel conceptual framework, distinguishing them from conventional treatments. We specifically conceptualize therapeutic elements, cognitive-affective and behavioral changes, and segment the notion of "dose" into distinct categories. This actionable framework provides a systematic basis for enhancing DTx research, design, and clinical effectiveness.
Fields of Study & Subjects
Digital Mental Health Interventions
Virtual Reality Applications and Impacts
Impact of Technology on Adolescents
Publication details
- Journal / source
- npj Digital Medicine
- Publisher
- Springer Science and Business Media LLC
- Volume
- 9
- Issue
- 1
- Publication date
- 5 March 2026
- Language
- EN