Surface functionalization strategies for polydiacetylene-based colorimetric sensors

Communications Chemistry 2026 Open access

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Authors: Brainy Happy Ana Tasiman, Rizky Aflaha, Wiyogo Prio Wicaksono, Ganjar Fadillah, Yuliyan Dwi Prabowo, Joan Daniel Prades, Erwin Peiner, Kuwat TRIYANA, Hutomo Suryo Wasisto
DOI: 10.1038/s42004-026-01913-y
Cited by: 6
References: 204

Abstract

Polydiacetylene (PDA)-based colorimetric sensors offer a promising platform for rapid and visual detection, through a chromatic transition from blue to red. However, their broader applications are hindered by challenges in sensitivity, selectivity, and stability. This review comprehensively overviews functionalization strategies to overcome existing limitations, including chemical modification with reactive groups, conjugation with specific ligands or receptors, and integration with nanomaterials. Alternative approaches are also discussed. The interplay between base materials, deposition methods, and functionalization efficiencies is emphasized. Furthermore, this review addresses remaining challenges, proposes feasible solutions, and offers insights into future strategic directions for creating more advanced PDA-based colorimetric sensors.

Fields of Study & Subjects

Polydiacetylene-based materials and applications Supramolecular Self-Assembly in Materials Antimicrobial agents and applications

Publication details

Journal / source
Communications Chemistry
Publisher
Springer Science and Business Media LLC
Volume
9
Issue
1
Pages
60–60
Publication date
30 January 2026
Language
EN