Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production

Nature Metabolism 2026

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Authors: Kimberly S. Huggler, Kyle M. Flickinger, Matthew H. Forsberg, Carlos A. Mellado Fritz, Gavin Chang, Meghan F. McGuire, Christian M. Capitini, Jason R. Cantor
DOI: 10.1038/s42255-025-01428-1
Cited by: 6
References: 99

Fields of Study & Subjects

Cancer Hypoxia and Metabolism Mitochondrial Function and Pathology ATP Synthase and ATPases Research

Publication details

Journal / source
Nature Metabolism
Publisher
Springer Science and Business Media LLC
Volume
8
Issue
1
Pages
215–236
Publication date
16 January 2026
Language
EN