Chronic stress drives liver cancer by impairing the hepatic kynurenine pathway and immune surveillance

Nature Metabolism 2026

View at publisher
Authors: Renhui Sun, Deyan Jiao, Wenjing Yuan, Hao Wang, Lingtong Ren, Zhendong Fu, N. Zhang, Xuetian Yue, Zhuanchang Wu, Chunyang Li, Huili Hu, M. Wang
+3 more Lifen Gao, Chunhong Ma, Xiaohong Liang
DOI: 10.1038/s42255-025-01430-7
Cited by: 14
References: 55

Fields of Study & Subjects

Tryptophan and brain disorders Cancer Stress Anesthesia and Immune Response Stress Responses and Cortisol

Publication details

Journal / source
Nature Metabolism
Publisher
Springer Science and Business Media LLC
Volume
8
Issue
1
Pages
196–214
Publication date
19 January 2026
Language
EN