Extracellular CD44 lactylation impairs CD8+ T cell function in KRAS-mutant colorectal cancer

Nature Metabolism 2026

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Authors: Yi Yang, Y. C. Xu, Xia Guo, Wen-Juan Gan, Wen-Xin Wu, Wei-Yi Shi, Xiaoshun He, Yi-Xuan Liu, Shan Wan, Zhi Jiang, Ying Liu, Xiuming Li

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Zu-Da Pan, X. Zhang, Yan Xu, Xubo Gao, L. B. Guo, Guideng Li, Hua Wu

DOI: 10.1038/s42255-026-01482-3

Cited by: 10

References: 66

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Proteoglycans and glycosaminoglycans research T-cell and B-cell Immunology

References 66