Targeted inhibition of FBXL2 confers susceptibility of HER2-negative breast cancer to trastuzumab deruxtecan

Nature Cancer 2026

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Authors: Jing Xu, Jiayi Liu, Yang Liu, Ting Huang, Yong Yi, Ruixiao Bai, Haorui Zheng, Xiaoli Chen, Jiexin Gao, Xin Lian, Rongtian Guo, Chuan Xu

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Qintong Li, Y. Zhang, Yang Cao, Peng Mi, Zhi-Xiong Jim Xiao, MengMeng Niu

DOI: 10.1038/s43018-025-01112-z

Cited by: 1

References: 67

Fields of Study & Subjects

HER2/EGFR in Cancer Research Click Chemistry and Applications Ubiquitin and proteasome pathways

References 67